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DHEA (dehydroepiandrosterone) is a hormone produced by your body's adrenal glands. DHEA levels decline with age, many reports associate DHEA with  positive support for anti-aging. DHEA is used by people who want to "reverse" aging and boost immunity, cognitive function, and muscle strength.

A growing body of research suggests that DHEA can prevent or reverse the diseases that anti-aging experts have identified as the most prominent markers of accelerated aging: atherosclerosis (hardening and clogging of the arteries), cancer, diabetes, and reduced immunity. Moreover, mounting evidence indicates that the level of DHEA in a person's blood is an excellent predictor not only of these age-related health problems but also of aging itself. "DHEA is undeniably one of the most crucial predictive factors in diagnosing aging-related diseases," according to Ronald Klatz, D.O., president of the American Academy of Anti-Aging Medicine.

DHEA is the most abundant hormone in your body. But production peaks at around age 20. From then on, your DHEA level decreases with age. By the time you reach 40, your body makes about half as much DHEA as it used to. By 65, output drops to 10 to 20 percent of optimum; by age 80, it plummets to less than 5 percent of optimum.

Because DHEA has such broad-spectrum effects, declining production makes itself known in every system, every organ, and every tissue of your body. The immune system is especially sensitive to diminishing DHEA output, opening the door not just to viruses, bacteria, and other microbes but also to free radicals and the Pandora's box of degenerative diseases they cause.

A number of studies have found that DHEA supplements may help people with depression, obesity, lupus, and adrenal insufficiency. DHEA may also improve skin in older people and help treat osteoporosis, vaginal atrophy, erectile dysfunction,  and some psychological conditions. Low DHEA levels are associated with aging and a number of diseases, such as anorexia, type 2 diabetes, and HIV. In older men, having low levels of DHEA is also associated with a higher chance of death.

_{REFERENCE
http://www.anti-agingmd.com/dhea.html
http://www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/dhea}